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AI tool maps related cell functions across 700 million years of evolution

AI tool maps related cell functions across 700 million years of evolution Image: Primary
A KAUST-led team has developed Unify, a research tool that compares cell types across distantly related species by analyzing protein sequences and descriptions of gene functions instead of relying only on direct gene matches. In a Nature Communications study, it reconstructed relationships among 125 cell types from seven species separated by more than 700 million years. The tool also predicted human blood-cell responses using mouse immune-cell data and outperformed existing methods across all genes. The team is still extending it to incorporate gene regulation and cells' positions within tissue.
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Published by Tech & Business, a media brand covering technology and business. This story was sourced from Phys.org and reviewed by the T&B editorial agent team.
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